London, Operation transplant (graft) throat using a deceased donor transplant and then developed with stem cells (stem cells) that the patient is usually developed in the laboratory.
But now doctors are able to do trachea transplant from a deceased donor using the patient's own stem cells directly in the throat of the patient without going through the planting in the laboratory.
Donor transplant done by taking the trachea from a deceased donor. Then the doctor will remove all the stem cells from the pedonor and leaves one network and replace them by growing the cells from stem cells (stem cells) of patients.
The operation was the first operation by injecting the trachea with a deceased donor stem cells from boys in England aged 10 years who directly implanted in his throat.
This operation is the development of the first trachea transplant in the world using stem cells in November 2008. Only difference, if the first of the donor trachea with the stem cell patients can not be done directly in the throat but in the laboratory.
Previous expert team from University College London, Florence in Italy and Barcelona, Spain who had throat first transplant using stem cells in 2008 which was also developed this technique to the case of the boy.
With this system the boy stem cells derived from bone marrow is ready for use in just four hours later. These cells will trigger regrowth of cells to create a normal trachea without the risk of transplantation such as rejection by the body.
This operation took place at Great Ormond Street Hospital, London. The boy has now been able to breathe alone and unable to speak normally.
This is the first time a child receives an organ transplant directly created by the stem cells directly in the throat. In previous operations throat cells grown in the laboratory prior to a few months before the implanted organ.
The boy has not announced his name will remain in the hospital to be monitored for development growth. It is expected that air pipes will be fully formed within two weeks. Meanwhile, other organs also expected to support.
"This is the first time a child is receiving treatment with stem cell organ stem the longest air route that had replaced that is about 7 cm in length," said Professor Martin Birchall, head of transplant regenerative medicine at University College London, as quoted by the Telegraph, on Monday (22 / 3 / 2010).
Professor Birchall added at this time he and the team is conducting further clinical trials to show that this concept could work well. Himself and the team also plans to do so in other organs, especially the larynx and esophagus.
The little boy was born with only a trachea of a millimeter so that makes it not able to breathe alone.
Previously he had undergone surgery to extend the rod teggorokannya with the help of metal materials for a year, but the metal is pierced large blood vessel that causes bleeding.
Emergency surgery was performed to repair the existing hole. But in November 2009, blood vessels penetrate the metal back, but the bleeding can be controlled. Finally, the surgeon was running out of viable options for care.
Prof. Elliot as director of services at Great Ormond Street trachea revealed patients can benefit greatly from this technique in the future. One of the benefits obtained are to reduce the risk of organ rejection by the body after surgery.
Someone doing an organ transplant throat because the organ is usually imperfect, damaged by illness such as tuberculosis. Graft is needed so that the patient had difficulty breathing and could not speak normally.
No comments:
Post a Comment